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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCB1
All Species:
22.73
Human Site:
Y444
Identified Species:
55.56
UniProt:
Q9NQ66
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ66
NP_056007.1
1216
138567
Y444
L
M
E
P
L
E
K
Y
P
L
E
S
G
V
P
Chimpanzee
Pan troglodytes
XP_001170216
1271
144286
Y499
L
M
E
P
L
E
K
Y
P
L
E
S
G
V
P
Rhesus Macaque
Macaca mulatta
XP_001116017
1216
138567
Y444
L
M
E
P
L
E
K
Y
P
L
E
S
G
V
P
Dog
Lupus familis
XP_542896
1210
138183
Y438
L
M
E
P
L
E
K
Y
P
L
E
S
G
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1B3
1216
138307
Y444
L
M
E
P
L
E
K
Y
P
L
E
S
G
V
P
Rat
Rattus norvegicus
P10687
1216
138326
Y444
L
M
E
P
L
E
K
Y
P
L
E
S
G
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513474
1217
138978
P444
M
E
P
L
E
K
Y
P
L
E
S
G
V
P
L
Chicken
Gallus gallus
Q2VRL0
637
72514
Frog
Xenopus laevis
Q32NH8
758
87399
D65
K
S
T
F
S
I
S
D
I
E
T
V
R
E
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
A503
A
N
S
V
D
A
K
A
A
Q
Q
V
G
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
99.1
92.5
N.A.
96.5
97.3
N.A.
92.5
21.6
23.1
N.A.
N.A.
39.9
N.A.
N.A.
N.A.
Protein Similarity:
100
95.3
99.5
94.9
N.A.
97.9
98.6
N.A.
95.7
34.4
35.1
N.A.
N.A.
57.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
0
0
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
0
0
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
10
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
10
60
0
10
60
0
0
0
20
60
0
0
10
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
70
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
10
70
0
0
0
0
0
0
0
0
% K
% Leu:
60
0
0
10
60
0
0
0
10
60
0
0
0
10
10
% L
% Met:
10
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
60
0
0
0
10
60
0
0
0
0
10
60
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
10
10
0
10
0
10
0
0
0
10
60
0
0
10
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
20
10
60
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _